Analytical Data
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Gene name
CREBZF
- Application
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Alternative Names
CREBZF；ZF;CREB/ATF bZIP transcription factor
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NS37
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Expression Region
1-354aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMRHSLTK LLAASGSNSP TRSESPEPAA TCSLPSDLTR AAAGEEETAA AGSPGRKQQF GDEGELEAGR GSRGGVAVRA PSPEEMEEEA IASLPGEETE DMDFLSGLEL ADLLDPRQPD WHLDPGLSSP GPLSSSGGGS DSGGLWRGDD DDEAAAAEMQ RFSDLLQRLL NGIGGCSSSS DSGSAEKRRR KSPGGGGGGG SGNDNNQAAT KSPRKAAAAA ARLNRLKKKE YVMGLESRVR GLAAENQELR AENRELGKRV QALQEESRYL RAVLANETGL ARLLSRLSGV GLRLTTSLFR DSPAGDHDYA LPVGKQKQDL LEEDDSAGGV CLHVDKDKVS VEFCSACARK ASSSLKM
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Molecular Weight
40 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CREBZF (Cyclic AMP Response Element-Binding Protein Zinc Finger) is a member of the CREB/ATF family of transcription factors, recognized for its role in regulating gene expression linked to stress responses, inflammation, and cellular growth. Recent studies highlight its significance in various physiological processes, including neuroprotection, metabolic regulation, and immune responses. Abnormal CREBZF expression has been implicated in numerous pathologies, including cancer, neurodegenerative diseases, and diabetes, suggesting its potential as a therapeutic target. The recombinant protein form of CREBZF allows for in-depth investigations into its structural and functional properties, facilitating the study of its interactions with other proteins and DNA. This research can provide insights into the mechanisms underlying its regulatory roles and the potential development of CREBZF-based interventions for diseases. By using techniques such as protein purification, functional assays, and structural analysis, scientists aim to elucidate the pathways that CREBZF influences, expanding our understanding of its contribution to cellular homeostasis and disease progression. Understanding the complexities of CREBZF’s functionality through recombinant protein studies is crucial for developing innovative strategies in biomedical research and therapeutics.
