Analytical Data
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基因名
CKMT2
- Application
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别名
CKMT2；Creatine kinase S-type. mitochondrial
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P17540
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表达区间
40-419aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSHMEVREQ PRLFPPSADY PDLRKHNNCM AECLTPAIYA KLRNKVTPNG YTLDQCIQTG VDNPGHPFIK TVGMVAGDEE SYEVFADLFD PVIKLRHNGY DPRVMKHTTD LDASKITQGQ FDEHYVLSSR VRTGRSIRGL SLPPACTRAE RREVENVAIT ALEGLKGDLA GRYYKLSEMT EQDQQRLIDD HFLFDKPVSP LLTCAGMARD WPDARGIWHN YDKTFLIWIN EEDHTRVISM EKGGNMKRVF ERFCRGLKEV ERLIQERGWE FMWNERLGYI LTCPSNLGTG LRAGVHVRIP KLSKDPRFSK ILENLRLQKR GTGGVDTAAV ADVYDISNID RIGRSEVELV QIVIDGVNYL VDCEKKLERG QDIKVPPPLP QFGKK
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分子量
46 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CKMT2, or mitochondrial creatine kinase 2, plays a critical role in cellular energy metabolism by facilitating the transfer of high-energy phosphate groups, thus maintaining ATP levels in muscle and brain tissues. Its function is crucial for optimal performance in energy-demanding activities and cellular homeostasis. Abnormalities in CKMT2 expression or function have been linked to various pathological conditions, including neurodegenerative diseases, heart failure, and muscle disorders. Research on CKMT2 recombinant protein has gained momentum due to its potential as a therapeutic target and its role in understanding energy metabolism disorders. By expressing and purifying CKMT2 in vitro, scientists can investigate its structural properties, enzymatic activity, and interaction with other cellular components. Moreover, recombinant CKMT2 can serve as a valuable tool for developing assays to screen for small molecules that modulate its activity, thereby paving the way for novel treatment strategies. The study of CKMT2 recombinant protein not only enhances our comprehension of mitochondrial function but also contributes to the broader understanding of metabolism-related diseases, potentially leading to innovative therapeutic approaches.
