Analytical Data
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基因名
NPNT
- Application
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别名
NPNT；EGFL6L；POEM；Nephronectin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y639
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表达区间
29-220aa
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氨基酸序列
QNEPRIVTSEEVIIRDSPVLPVTLQCNLTSSSHTLTYSYWTKNGVELSAT RKNASNMEYRINKPRAEDSGEYHCVYHFVSAPKANATIEVKAAPDITGHK RSENKNEGQDATMYCKSVGYPHPDWIWRKKENGMPMDIVNTSGRFFIINK ENYTELNIVNLQITEDPGEYECNATNAIGSASVVTVLRVRSHVDHHHHHH
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分子量
23 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NPNT (Nephron Progenitor-Niche Transcription Factor) is a critical protein involved in kidney development and nephron formation. The study of NPNT is particularly important due to its role in regulating nephrogenesis, the process by which nephrons, the functional units of the kidney, are formed. Understanding NPNT's function and mechanism offers insights into kidney biology and potential implications for regenerative medicine and treatment of renal diseases. Recent research has highlighted NPNT's involvement in the signaling pathways that govern cell differentiation and proliferation in the nephron progenitor niche. Investigating the dynamics of NPNT expression and its interaction with other key factors within the kidney microenvironment can pave the way for new therapeutic strategies aimed at enhancing kidney repair or regeneration in the context of conditions such as congenital disorders or chronic kidney disease. Thus, NPNT serves as a promising target for further exploration in the fields of developmental biology and nephrology, where its manipulation could lead to innovative approaches to kidney health and disease management.
