Analytical Data
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基因名
CCDC69
- Application
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别名
CCDC69；Coiled-coil domain-containing Protein 69
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A6NI79
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表达区间
1-296aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMGCRHSR LSSCKPPKKK RQEPEPEQPP RPEPHELGPL NGDTAITVQL CASEEAERHQ KDITRILQQH EEEKKKWAQQ VEKERELELR DRLDEQQRVL EGKNEEALQV LRASYEQEKE ALTHSFREAS STQQETIDRL TSQLEAFQAK MKRVEESILS RNYKKHIQDY GSPSQFWEQE LESLHFVIEM KNERIHELDR RLILMETVKE KNLILEEKIT TLQQENEDLH VRSRNQVVLS RQLSEDLLLT REALEKEVQL RRQLQQEKEE LLYRVLGANA SPAFPLAPVT PTEVSFLAT
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分子量
37 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCDC69, or coiled-coil domain containing 69, is a protein that has garnered attention in recent years due to its potential roles in cellular processes and disease mechanisms. Research indicates that CCDC69 is involved in cilia formation, which are essential cellular organelles for signal transduction and maintaining cellular homeostasis. Defects in ciliary structure and function are linked to a group of disorders known as ciliopathies, which can manifest in various clinical features, including developmental issues and organ dysfunction. Additionally, CCDC69 has been associated with the regulation of primary cilia and the Hedgehog signaling pathway, which plays a critical role in embryonic development and tissue patterning. The study of CCDC69, particularly through the use of recombinant protein techniques, allows researchers to explore its structural characteristics, interaction partners, and functional mechanisms in greater depth. By elucidating the role of CCDC69 in both normal physiology and pathological conditions, researchers aim to gather insights that could lead to novel therapeutic strategies for diseases associated with ciliary dysfunction. Thus, the investigation of CCDC69 not only enhances our understanding of fundamental biological processes but also holds promise for addressing complex health challenges linked to organ development and function.
