Analytical Data
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Gene name
CCDC69
- Application
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Alternative Names
CCDC69；Coiled-coil domain-containing Protein 69
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
A6NI79
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Expression Region
1-296aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMGCRHSR LSSCKPPKKK RQEPEPEQPP RPEPHELGPL NGDTAITVQL CASEEAERHQ KDITRILQQH EEEKKKWAQQ VEKERELELR DRLDEQQRVL EGKNEEALQV LRASYEQEKE ALTHSFREAS STQQETIDRL TSQLEAFQAK MKRVEESILS RNYKKHIQDY GSPSQFWEQE LESLHFVIEM KNERIHELDR RLILMETVKE KNLILEEKIT TLQQENEDLH VRSRNQVVLS RQLSEDLLLT REALEKEVQL RRQLQQEKEE LLYRVLGANA SPAFPLAPVT PTEVSFLAT
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Molecular Weight
37 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCDC69, or coiled-coil domain containing 69, is a protein that has garnered attention in recent years due to its potential roles in cellular processes and disease mechanisms. Research indicates that CCDC69 is involved in cilia formation, which are essential cellular organelles for signal transduction and maintaining cellular homeostasis. Defects in ciliary structure and function are linked to a group of disorders known as ciliopathies, which can manifest in various clinical features, including developmental issues and organ dysfunction. Additionally, CCDC69 has been associated with the regulation of primary cilia and the Hedgehog signaling pathway, which plays a critical role in embryonic development and tissue patterning. The study of CCDC69, particularly through the use of recombinant protein techniques, allows researchers to explore its structural characteristics, interaction partners, and functional mechanisms in greater depth. By elucidating the role of CCDC69 in both normal physiology and pathological conditions, researchers aim to gather insights that could lead to novel therapeutic strategies for diseases associated with ciliary dysfunction. Thus, the investigation of CCDC69 not only enhances our understanding of fundamental biological processes but also holds promise for addressing complex health challenges linked to organ development and function.
