Analytical Data
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Gene name
CCDC43
- Application
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Alternative Names
CCDC43；Coiled-coil domain-containing Protein 43
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96MW1
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Expression Region
1-224aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAAPSEV AAIAPGEGDG GGGGFGSWLD GRLEALGVDR AVYGAYILGI LQEEEEEEKL DALQGILSAF LEEDSLLNIC KEIVERWSET QNVVTKVKKE DEVQAIATLI EKQAQIVVKP RMVSEEEKQR KAALLAQYAD VTDEEDEADE KDDSGATTMN IGSDKLLFRN TNVEDVLNAR KLERDSLRDE SQRKKEQDKL QRERDKLAKQ ERKEKEKKRT QRGERKR
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Molecular Weight
27 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCDC43, or Coiled-Coil Domain Containing 43, is a protein that has garnered attention in recent years due to its potential roles in both normal physiological processes and various pathologies. It is primarily recognized for its involvement in the cellular mechanisms underlying ciliary function and basal body assembly, which are critical for proper cellular signaling and motility. Dysregulation of ciliary function is linked to a spectrum of diseases, including ciliopathies, which can affect multiple organ systems and lead to significant health issues. Research has indicated that CCDC43 may play a role in mediating interactions between cilia and the cytoskeleton, influencing cell adhesion and communication. Its importance in development and cell cycle regulation further emphasizes the need for a detailed understanding of CCDC43's structure and function. Recombinant CCDC43 protein studies are essential for elucidating its biochemical properties, molecular interactions, and the pathways in which it participates. This research can contribute to the identification of therapeutic targets for diseases associated with ciliary dysfunction and advance our understanding of cellular dynamics in health and disease. As such, CCDC43 represents a promising focus for both basic research and potential clinical applications.
