Cat: PA1000-9184

Recombinant Human TACR1 Protein,His

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Analytical Data

  • 基因名

    TACR1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    TACR1;NK1R;TAC1R;Substance-P receptor

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P25103

  • 表达区间

    1-29aa

  • 氨基酸序列

    MDNVLPVDSDLSPNISTNTSEPNQFVQPA

  • 分子量

    30.1 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

TACR1, or Tachykinin Receptor 1, is a G-protein coupled receptor primarily involved in mediating the effects of neuropeptides such as substance P and neurokinin A. It plays a crucial role in numerous physiological processes, including pain perception, inflammation, and smooth muscle contraction. The receptor is predominantly expressed in the central and peripheral nervous systems, implicating it in various pathological conditions such as anxiety, depression, and neurodegenerative diseases. Research into TACR1 recombinant proteins has gained significant interest due to their potential therapeutic applications. The ability to produce TACR1 in a recombinant form allows for detailed functional studies and the development of selective ligands that can modulate receptor activity. Additionally, this research facilitates the exploration of TACR1 as a target for drug discovery, aiming to design novel treatments for disorders where tachykinin signaling is dysregulated. Understanding TACR1’s structure and function at a molecular level enables scientists to identify key mechanisms of action and inform the development of strategies for clinical intervention. Overall, the study of TACR1 recombinant proteins is essential for elucidating the complexities of tachykinin signaling and advancing therapeutic approaches in neurology and pain management.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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