Analytical Data
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基因名
CAPZA2
- Application
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别名
CAPZA2；F-actin-capping Protein subunit alpha-2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P47755
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表达区间
1-286aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMADLEEQ LSDEEKVRIA AKFIIHAPPG EFNEVFNDVR LLLNNDNLLR EGAAHAFAQY NLDQFTPVKI EGYEDQVLIT EHGDLGNGKF LDPKNRICFK FDHLRKEATD PRPCEVENAV ESWRTSVETA LRAYVKEHYP NGVCTVYGKK IDGQQTIIAC IESHQFQAKN FWNGRWRSEW KFTITPSTTQ VVGILKIQVH YYEDGNVQLV SHKDIQDSLT VSNEVQTAKE FIKIVEAAEN EYQTAISENY QTMSDTTFKA LRRQLPVTRT KIDWNKILSY KIGKEMQNA
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分子量
35 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CAPZA2, a member of the CAPZ protein family, plays a critical role in regulating actin dynamics by capping the barbed ends of actin filaments, thereby influencing cellular processes such as motility, shape, and division. Its function is vital in various biological contexts, including muscle development, neuronal signaling, and cell migration. Dysregulation of CAPZA2 has been linked to several diseases, such as cancer and neurodegenerative disorders, underscoring its potential as a therapeutic target. Research on CAPZA2 recombinant protein focuses on understanding its structure-function relationships and biochemical properties, enabling the exploration of its role in cellular behavior at the molecular level. Furthermore, recombinant CAPZA2 can serve as a valuable tool for biochemical assays and drug screening, facilitating the identification of novel modulators that can influence actin dynamics in disease contexts. Given the importance of actin filament regulation in numerous physiological and pathological processes, the study of CAPZA2 represents a promising avenue for uncovering fundamental insights into cellular mechanics and the development of innovative therapeutic strategies.
