Analytical Data
-
基因名
RRM2B
- Application
-
别名
TP53-inducible ribonucleotide reductase M2 B p53-inducible ribonucleotide reductase small subunit 2-like protein
-
种属
Human
-
表达系统
E. coli
-
标签
N- GST
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q7LG56
-
表达区间
1-351aa
-
分子量
67.7 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RRM2B, a critical component of the ribonucleotide reductase complex, plays a vital role in DNA synthesis and repair by regulating the conversion of ribonucleotides into deoxyribonucleotides, which are essential for DNA replication and cellular proliferation. Mutations in the RRM2B gene have been linked to a range of human diseases, including mitochondrial disorders and certain types of cancer, highlighting its importance in maintaining genomic stability. The study of RRM2B recombinant proteins has gained significant attention in the fields of molecular biology and biochemistry, as understanding its structure and function can provide insights into the mechanisms underlying DNA metabolism and cellular responses to oxidative stress. Through the expression and characterization of RRM2B recombinant proteins, researchers aim to elucidate its enzymatic properties, interaction with other cellular components, and potential regulatory pathways, ultimately contributing to the development of novel therapeutic strategies targeting RRM2B-related conditions. Advances in recombinant protein technology and analytical techniques enable detailed investigation of RRM2B, stressing its relevance in both basic research and clinical applications.
