Analytical Data
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基因名
ARPC3
- Application
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别名
ARPC3；ARC21；Actin-related Protein 2/3 complex subunit 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15145
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表达区间
1-178aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMPAYHSS LMDPDTKLIG NMALLPIRSQ FKGPAPRETK DTDIVDEAIY YFKANVFFKN YEIKNEADRT LIYITLYISE CLKKLQKCNS KSQGEKEMYT LGITNFPIPG EPGFPLNAIY AKPANKQEDE VMRAYLQQLR QETGLRLCEK VFDPQNDKPS KWWTCFVKRQ FMNKSLSGPG Q
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分子量
23 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ARPC3, a crucial component of the Arp2/3 complex, plays a significant role in regulating actin cytoskeleton dynamics, which is vital for various cellular processes, including migration, adhesion, and division. The Arp2/3 complex nucleates new actin filaments and generates branched actin networks, enabling cells to change shape and move efficiently. Research on ARPC3 recombinant protein has gained momentum due to its implications in understanding fundamental cellular mechanisms and its potential impact on various diseases, including cancer metastasis and immunological disorders. Recombinant ARPC3 provides a platform for studying the complex's regulatory mechanisms, investigating actin polymerization, and identifying potential therapeutic targets. By producing ARPC3 in a controlled environment, scientists can analyze its interactions with other proteins, assess its structural properties, and elucidate its role in cellular signaling pathways. Moreover, the study of ARPC3 and its functions can contribute to the development of innovative strategies for combating diseases that involve aberrant actin dynamics. As a result, ARPC3 recombinant protein serves as an essential tool for advancing our understanding of actin-related cellular processes and their implications in health and disease.
