Analytical Data
-
Gene name
ARL1
- Application
-
Alternative Names
ARL1；ADP-ribosylation factor-like Protein 1
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q96RJ2
-
Expression Region
1-196aa
-
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSVNSRGHK AEAQVVMMGL DSAGKTTLLY KLKGHQLVET LPTVGFNVEP LKAPGHVSLT LWDVGGQAPL RASWKDYLEG TDILVYVLDS TDEARLPESA AELTEVLNDP NMAGVPFLVL ANKQEAPDAL PLLKIRNRLS LERFQDHCWE LRGCSALTGE GLPEALQSLW SLLKSRSCMC LQARAHGAER GDSKRS
-
Molecular Weight
24 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ARL1 (ADP-ribosylation factor-like protein 1) is a member of the Arf (ADP-ribosylation factor) family, which plays a crucial role in intracellular trafficking and membrane dynamics. It is implicated in various cellular processes, including endocytosis, membrane fusion, and protein transport. The study of ARL1 is particularly pertinent due to its involvement in the regulation of the Golgi apparatus and its potential links to disease mechanisms, such as cancer and neurodegenerative disorders. Research has shown that ARL1 interacts with specific effectors and regulates the dynamics of membrane-bound compartments. Moreover, it has been suggested that aberrations in ARL1 function can disrupt cellular homeostasis and contribute to pathological states. The reconstitution of ARL1 as a recombinant protein enables detailed biophysical and biochemical analyses, allowing researchers to dissect its functional roles and interactions at the molecular level. Protein-protein interaction assays, localization studies, and functional assays are commonly employed to elucidate ARL1's mechanisms of action. Understanding the structural and functional properties of ARL1 is essential not only for basic cell biology but also for therapeutic applications, especially in targeting diseases associated with its dysregulation. Therefore, the exploration of ARL1 and its recombinant forms provides valuable insights into the fundamental processes underlying cellular organization and highlights potential avenues for intervention in related diseases.
