Analytical Data
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Gene name
POU4F2
- Application
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Alternative Names
Brain-specific homeobox/POU domain protein 3B (Brain-3B) (Brn-3B) (BRN3B)
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Species
Human
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q12837
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Expression Region
1-265aa
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Molecular Weight
36.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
POU4F2, also known as Brn-3b, is a member of the POU (Pittsburg Paired Box) transcription factor family that plays a crucial role in the development and function of neural tissues, particularly in sensory neurons of the retina and dorsal root ganglia. Its expression is linked to neuronal differentiation and survival, making it a key player in neurodevelopmental processes. Given its vital functions, dysregulation of POU4F2 has been implicated in various neurodegenerative diseases and sensory disorders. Research into recombinant POU4F2 protein has gained traction as scientists aim to elucidate its molecular mechanisms and interactions within neuronal pathways. By producing recombinant POU4F2, researchers can study its structural properties, assess its binding affinity to DNA, and explore its role in gene regulation. Experimental models utilizing this protein can provide insights into its involvement in neuronal health and disease, with potential therapeutic implications. Understanding POU4F2 at a molecular level may further contribute to the development of targeted treatments for conditions associated with its dysfunction, highlighting the importance of continued research in this domain.
