Analytical Data
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基因名
ANXA1
- Application
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别名
ANXA1；ANX1；LPC1；Annexin A1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P04083
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表达区间
1-346aa
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氨基酸序列
MAMVSEFLKQAWFIENEEQEYVQTVKSSKGGPGSAVSPYPTFNPSSDVAA LHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQETGKPLDETLKKAL TGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRTNKEIR DINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLAD SDARALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNK VLDLELKGDIEKCLTAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIM VSRSEIDMNDIKAFYQKMYGISLCQAILDETKGDYEKILVALCGGN
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ANXA1, or Annexin A1, is a member of the annexin family of proteins, known for its role in various cellular processes such as inflammation, apoptosis, and cell signaling. Its significance has been highlighted in several physiological and pathological conditions, including cancer, where it appears to influence tumor growth and metastasis. Research has shown that ANXA1 exerts anti-inflammatory effects, making it a potential target for therapeutic interventions. The recombinant production of ANXA1 protein allows for in-depth studies of its structure-function relationship and its interactions with other cellular molecules. By utilizing recombinant DNA technology, researchers can generate large quantities of purified ANXA1, facilitating both in vitro and in vivo experiments. Such studies are essential for understanding the precise biological role of ANXA1 and its potential as a biomarker or therapeutic target. Recent advances in proteomics and molecular biology have enhanced our ability to manipulate and study this protein, paving the way for novel therapeutic strategies aimed at modulating its activity in diseases characterized by inflammation or abnormal cell proliferation.
