Analytical Data
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基因名
RSPO2
- Application
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别名
(Roof plate-specific spondin-2)(hRspo2)
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种属
Human
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表达系统
E. coli
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标签
C- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6UXX9
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表达区间
22-205aa
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分子量
22.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RSPO2 (R-spondin 2) is a member of the R-spondin family of secreted proteins that play crucial roles in the regulation of the Wnt signaling pathway, which is vital for various biological processes, including embryonic development, tissue homeostasis, and stem cell maintenance. Mutations or dysregulation of RSPO2 have been implicated in several diseases, including certain types of cancer and developmental disorders. Research on RSPO2 has increased due to its potential as a therapeutic target and its involvement in enhancing regenerative medicine strategies. Furthermore, understanding the structural and functional properties of RSPO2 can provide insights into its interactions with other proteins and signaling pathways. This has led to efforts in the recombinant production of RSPO2, allowing for detailed biochemical and biophysical analyses. Recombinant RSPO2 is utilized in various studies to elucidate its role in augmenting Wnt signaling, assessing its effects on stem cell proliferation and differentiation, and investigating its potential in organoid culture systems. Consequently, the study of RSPO2 not only sheds light on fundamental biological mechanisms but also holds promise for advancements in regenerative therapies and cancer treatments.
