Analytical Data
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基因名
KRT13
- Application
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别名
(Cytokeratin-13)(CK-13)(Keratin-13)(K13)
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种属
Human
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P13646
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表达区间
1-458aa
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分子量
57.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KRT13, or keratin 13, is a type of intermediate filament protein predominantly expressed in the stratified squamous epithelium, particularly in the mucosal surfaces such as the oral cavity and esophagus. This protein plays a crucial role in maintaining cellular integrity and providing mechanical resilience to epithelial tissues. Mutations or dysregulation of KRT13 have been implicated in various pathological conditions, including skin disorders and epithelial cancers, highlighting its significance in both health and disease. Recent studies have focused on the recombinant production of KRT13 to facilitate in-depth functional analyses and explore its potential roles in cell biology and tissue engineering. By utilizing recombinant DNA technology, researchers can generate large quantities of KRT13 protein, which allows for advanced studies into its structural properties, interactions with other cellular components, and its role in epithelial cell differentiation and development. This line of research holds promise for understanding the underlying mechanisms of epithelial disorders and developing novel therapeutic strategies targeting KRT13-related pathways. Furthermore, the recombinant KRT13 protein can serve as a valuable tool in the development of biomaterials and regenerative medicine applications, where its properties may be leveraged to enhance tissue repair and regeneration. Overall, the investigation of KRT13 recombinant protein represents a significant advance in the field of molecular biology and biomedical research, providing insights that could lead to innovative treatments for various epithelial conditions.












