Analytical Data
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基因名
ALS3
- Application
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别名
3D9 antigen Adhesin 3
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种属
Candida albicans
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表达系统
E. coli
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标签
N- His-B2M & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O74623
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表达区间
918-1119aa
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分子量
37.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by the degeneration of motor neurons, leading to muscle weakness and ultimately paralysis. Research has identified various genetic factors contributing to ALS, among which the ALS3 gene, associated with the 9p21 locus, has gained attention. Studies suggest that mutations in the ALS3 gene can disrupt normal cellular functions, potentially leading to neuronal damage. The encoding of the ALS3 recombinant protein aims to better understand its structure and function within cellular pathways, especially relating to neuroprotection and synaptic maintenance. By analyzing the characteristics and interactions of ALS3, researchers hope to uncover therapeutic targets or biomarkers that could aid in the diagnosis and treatment of ALS. Additionally, understanding the role of ALS3 in the context of ALS may provide insights into the shared molecular mechanisms underlying neurodegenerative diseases, paving the way for novel intervention strategies and improved patient outcomes. Through the development of ALS3 recombinant protein, the scientific community can further investigate its implications in cellular stress responses and neuroinflammation, all critical components in the pathology of ALS and other related disorders.
