Analytical Data
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基因名
Adgre1
- Application
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别名
(Cell surface glycoprotein F4/80)(EGF-like module receptor 1)(EGF-like module-containing mucin-like hormone receptor-like 1)(EMR1 hormone receptor)
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种属
Mouse
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q61549
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表达区间
28-644aa
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分子量
74.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Adgre1, also known as F4/80, is a member of the epidermal growth factor (EGF)-like family of proteins and serves as a significant marker for macrophages. Its expression is predominantly observed in tissue-resident macrophages and plays a crucial role in immune system modulation, inflammation, and tissue homeostasis. Research into Adgre1 recombinant protein has intensified, owing to its pivotal role in immunological responses and potential therapeutic implications in various diseases. Studies have shown that Adgre1 is involved in the regulation of macrophage activation and the phagocytosis process, influencing tissue repair and homeostasis. Understanding its structure and function through recombinant protein expression can provide insights into macrophage biology and their interaction with other immune cells. Furthermore, Adgre1's association with chronic inflammatory conditions and cancer progression underscores its potential as a therapeutic target. The development of Adgre1 recombinant proteins facilitates deeper exploration of its signaling pathways and mechanisms, paving the way for novel interventions in macrophage-related diseases. Extensive characterization and application of Adgre1 recombinant proteins can advance our knowledge in both basic and translational research, potentially leading to innovative strategies for modulating immune responses in various pathological contexts.
