Analytical Data
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基因名
AIFM1
- Application
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别名
AIFM1；AIF；PDCD8；Apoptosis-inducing factor 1. mitochondrial
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95831
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表达区间
121-613aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMEEVPQDKAPSHVPFLLIGGGTAAFAAARS IRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWNGK ERSIYFQPPSFYVSAQDLPHIENGGVAVLTGKKVVQLDVRDNMVKLNDGS QITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFRKIGDFRSLEKISRE VKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKILPEYLS NWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVG LEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGR RRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVD SSLPTVGVFAKATAQDNPKSATEQSGTGIRSESETESEASEITIPPSTPA VPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHE DLNEVAKLFNIHED
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分子量
67 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
AIFM1, or Apoptosis Inducing Factor Mitochondria-associated 1, is a pivotal protein involved in regulating apoptosis and mitochondrial function. Research into AIFM1 has gained significant momentum due to its essential roles in cellular processes and its implications in various diseases, particularly in neurodegenerative disorders and cancers. Mutations in the AIFM1 gene have been associated with X-linked intellectual disability and syndromic conditions, highlighting its importance in neural development and function. The characterization of AIFM1 recombinant protein has become crucial for elucidating its structural and functional properties, which could provide insights into its mechanism of action in programmed cell death and mitochondrial dynamics. Moreover, understanding AIFM1's interactions with other cellular components can pave the way for therapeutic strategies aimed at modulating its activity in disease contexts. As the exploration of AIFM1 continues, the development of recombinant protein studies not only enhances our comprehension of its biological significance but also fosters potential avenues for clinical applications in treating conditions linked to AIFM1 dysfunction.
