Cat: IPD-X41404

Recombinant Pacifastacus leniusculus Astakine Protein ,His & Myc

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Analytical Data

  • Gene name

    Astakine

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    (Prokineticin-like cytokine)

  • Species

    Pacifastacus leniusculus

  • Source

    E. coli

  • Tag

    N- His & C- Myc

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q56R11

  • Expression Region

    23-104aa

  • Molecular Weight

    16.2 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Astakine is a novel protein identified in the context of astacidae, or freshwater crayfish, that has garnered interest due to its potential roles in growth regulation and immune responses. Research into Astakine has emerged from the need to understand the molecular mechanisms underlying the development and physiological processes in crustaceans, as these organisms are important both ecologically and economically. Initial studies have indicated that Astakine may be involved in the regulation of insulin signaling and the immune system, which are crucial for the overall health and growth of crustaceans. The protein is believed to function similarly to other known hormones and signaling molecules, offering insights into the complex interplay between endocrine signaling and adaptive immunity in invertebrates. A deeper understanding of Astakine's structure and function could pave the way for biotechnological applications, including enhancements in aquaculture practices, while also contributing to broader knowledge in evolutionary biology and comparative immunology. As research progresses, the characterization of Astakine's activity may lead to novel interventions aimed at improving the resilience and growth of economically significant aquatic species. This ongoing investigation highlights the relevance of studying lesser-known proteins within the context of global food security and biodiversity conservation.

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