Analytical Data
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Gene name
TCF7
- Application
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Alternative Names
(TCF-7)(T-cell-specific transcription factor 1)(T-cell factor 1)(TCF-1)
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Species
Human
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P36402
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Expression Region
1-384aa
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Molecular Weight
49.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TCF7, or T-cell factor 7, is a transcription factor that plays a crucial role in the Wnt signaling pathway, which is essential for various biological processes, including development, cell proliferation, and differentiation. This pathway influences stem cell maintenance and tissue homeostasis, and aberrations in Wnt signaling have been implicated in several diseases, including cancer. The study of TCF7 and its recombinant protein is vital as it offers insights into the molecular mechanisms underlying these processes. Moreover, TCF7 has been identified as a critical factor in regulating immune responses and has potential implications in immunotherapy. By generating and studying recombinant TCF7 protein, researchers aim to elucidate its structural and functional properties, explore its interaction with other signaling molecules, and understand its role in gene regulation. This knowledge could lead to the development of targeted therapies for Wnt-related disorders and enhance our understanding of immune regulation. Thus, the research on recombinant TCF7 serves not only to clarify its biological significance but also to identify novel therapeutic avenues for treating diseases associated with aberrant Wnt signaling and immune dysregulation.
