Analytical Data
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基因名
ns8
- Application
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别名
/
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种属
Human Novel Coronavirus
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P0DTC8
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表达区间
16-121aa
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分子量
16.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The NS8 protein plays a critical role in the lifecycle of various viruses, particularly within the genus Flavivirus, which includes notable pathogens such as the dengue virus and Zika virus. Initially identified as a non-structural protein, NS8 has garnered attention due to its involvement in viral replication and modulation of host immune responses. Studies have suggested that NS8 is implicated in the formation of viral replication complexes and the suppression of interferon signaling, making it a key factor in viral pathogenicity. Furthermore, researchers have explored the potential of NS8 as a target for antiviral drug development and as a candidate for vaccine formulation, given its immunogenic properties and role in the viral lifecycle. The complexity of NS8's interactions with host cellular mechanisms and its evolutionary adaptations have led to ongoing investigations aimed at defining its structural characteristics and functional implications. Understanding NS8 is essential for developing effective therapeutic strategies and enhancing vaccine efficacy against flavivirus infections, thereby addressing significant public health challenges posed by these emerging and re-emerging viral diseases.
