Analytical Data
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Gene name
lprG
- Application
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Alternative Names
27 kDa lipoprotein;Antigen P27;Lipoprotein LprG;Triacylglyceride transfer protein LprG
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Species
Mycobacterium tuberculosis
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P9WK44
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Expression Region
27-236aa
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Molecular Weight
29.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LprG is a lipoprotein found in Mycobacterium tuberculosis, the bacterium responsible for tuberculosis (TB). This protein is part of a larger family of lipoproteins crucial for the pathogen's survival and virulence within the host. The study of LprG has gained considerable interest due to its role in modulating the host immune response and its involvement in the transport of lipid molecules that are essential for the bacterium's cell envelope integrity. Research has shown that LprG interacts with a variety of host factors, influencing macrophage function and contributing to the survival of the bacteria within immune cells. Moreover, LprG is implicated in the regulation of the immune response, potentially aiding the bacterium in evading detection by the host's immune system. Understanding the structure and function of LprG, particularly in the context of its interactions with host molecules, may reveal new therapeutic targets for treating TB. The recombinant production of LprG in laboratory settings allows for detailed biochemical and structural studies, which are essential for elucidating its mechanism of action. Insights gained from such research could help in the design of novel vaccines or drugs to combat TB, a disease that remains a significant global health challenge, particularly in drug-resistant forms. Therefore, the investigation of LprG not only enhances our understanding of Mycobacterium tuberculosis biology but also has important implications for public health and disease management.
