Analytical Data
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基因名
SDH1
- Application
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别名
SDH1; MGG_05059Scytalone dehydratase; SD; SDH; EC 4.2.1.94
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种属
Magnaporthe oryzae
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P56221
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表达区间
1-172aa
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分子量
36.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SDH1, also known as succinate dehydrogenase subunit A, plays a crucial role in the tricarboxylic acid (TCA) cycle and the electron transport chain, linking mitochondrial respiration to cellular metabolism. Dysregulation of SDH1 has been implicated in various pathological conditions, including certain types of cancer, mitochondrial diseases, and metabolic disorders. The study of SDH1 recombinant protein is significant because it allows for detailed investigation of its biochemical properties, interactions, and regulatory mechanisms within the cell. Advanced techniques such as site-directed mutagenesis and protein crystallization enable researchers to elucidate the structural and functional aspects of SDH1, facilitating the understanding of its role in tumorigenesis and metabolic regulation. Moreover, recombinant SDH1 can be used to explore therapeutic strategies aimed at modulating its activity or targeting related pathways, presenting potential avenues for treating diseases associated with aberrant SDH1 function. By providing insights into the molecular basis of SDH1's activity, research on its recombinant form contributes to the broader understanding of mitochondrial function and its implications in health and disease.
