Cat: IPD-X41290

Recombinant Human TAF7L Protein ,His & Myc

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Analytical Data

  • Gene name

    TAF7L

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Cancer/testis antigen 40 (CT40) (RNA polymerase II TBP-associated factor subunit Q) (TATA box-binding protein-associated factor 50 kDa) (Transcription initiation factor TFIID 50 kDa subunit)

  • Species

    Human

  • Source

    E. coli

  • Tag

    N- His & C- Myc

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q5H9L4

  • Expression Region

    1-302aa

  • Molecular Weight

    42.2 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

TAF7L (TATA-box binding protein associated factor 7-like) is a member of the TAF family associated with the general transcription factor TFIID, crucial for RNA polymerase II-mediated transcription. This protein plays a significant role in the regulation of gene expression, particularly in germ cell development and spermatogenesis. Research has shown that TAF7L is essential for the proper formation of the transcriptional machinery in male germ cells and is implicated in the epigenetic regulation of gene expression during development. Its dysfunction is linked to various reproductive disorders and infertility, making it a target for studies aiming to understand male reproductive health better. In recent years, the recombination and expression of TAF7L protein have garnered attention to elucidate its functional mechanisms further and potential therapeutic applications. Investigating the biochemical properties and interactions of TAF7L within the transcriptional complex provides insights into its role in gene regulation and may unveil novel strategies to tackle infertility issues and other related disorders.

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