Analytical Data
-
Gene name
RGS2
- Application
-
Alternative Names
Cell growth-inhibiting gene 31 protein;G0/G1 switch regulatory protein 8
-
Species
Human
-
Source
E. coli
-
Tag
N- His-SUMO
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P41220
-
Expression Region
1-211aa
-
Molecular Weight
40.4 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RGS2 (Regulator of G protein signaling 2) is a member of the RGS protein family that plays a crucial role in modulating G protein-coupled receptor (GPCR) signaling pathways, which are essential for various physiological processes, including cardiovascular function, neuronal signaling, and immune response. Research has shown that RGS2 is a key regulator of the β-adrenergic signaling pathway, influencing heart rate and blood pressure regulation, thereby implicating it in cardiovascular diseases. Its dysregulation has been associated with conditions such as hypertension and anxiety disorders. Given its significant role in these pathways, RGS2 has garnered interest as a potential therapeutic target. The study of RGS2 recombinant proteins enables a deeper understanding of its functional mechanisms and interactions with other signaling molecules. Through the expression and purification of RGS2, researchers can analyze its structure-function relationship, validate its role in the signaling cascade, and explore its potential as a biomarker or drug target. With ongoing advancements in recombinant protein technologies, including improved expression systems and purification techniques, RGS2 research aims to unlock new insights into GPCR-mediated signaling and to provide novel therapeutic strategies for diseases linked to dysregulated RGS2 activity.
