Analytical Data
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基因名
MRPL12
- Application
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别名
5c5-2
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P52815
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表达区间
1-198aa
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分子量
43.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRPL12, a mitochondrial ribosomal protein, plays a crucial role in protein synthesis within the mitochondria, which are essential for cellular energy production and metabolic regulation. Recent studies have highlighted its importance in various cellular processes, including apoptosis, oxidative stress response, and mitochondrial biogenesis. Given the role of mitochondrial dysfunction in numerous diseases, including neurodegenerative disorders and cancer, understanding the function and regulation of MRPL12 can provide insights into therapeutic targets for these conditions. Researchers have been investigating the structural and functional properties of MRPL12 through techniques such as recombinant protein expression, which enables the study of its interactions with other mitochondrial components and ribosomal subunits. Characterizing MRPL12's function may reveal significant details about mitochondrial dynamics and its implications in health and disease, ultimately contributing to the development of novel treatment strategies aimed at enhancing mitochondrial function or correcting defects associated with MRPL12 deficiency. This research emphasizes the critical necessity of investigating mitochondrial proteins like MRPL12 to unravel the complex web of cellular mechanisms that underpin normal physiology and pathological states.












