Analytical Data
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基因名
KRT17
- Application
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别名
Cytokeratin-17 ;CK-17Keratin-17 ;K17
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种属
Bovine
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A1L595
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表达区间
1-441aa
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分子量
64.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KRT17, or Keratin 17, is a type of intermediate filament protein that plays a crucial role in the structural integrity and functionality of epithelial cells. Its expression is typically upregulated in response to various stressors, including mechanical injury and inflammation, making it a key marker in wound healing and tissue repair processes. Research into KRT17 has gained traction due to its involvement in a range of pathological conditions, including skin disorders, cancer, and inflammatory diseases. For instance, elevated KRT17 levels have been observed in certain carcinomas, suggesting its potential role in tumorigenesis and as a prognostic marker. Furthermore, KRT17 has been implicated in the regulation of cell proliferation, differentiation, and migration, which are vital for maintaining homeostasis in epithelial tissues. As a result, the study of KRT17 recombinant protein has become an important focus within cell biology and translational medicine. By exploring its molecular functions and interactions within cellular pathways, researchers aim to identify novel therapeutic targets and strategies for treating diseases characterized by altered keratin expression. The growing body of evidence surrounding KRT17 highlights its significance in both normal physiology and disease states, prompting continued investigation into its potential applications in clinical settings.
