Analytical Data
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基因名
KCNAB2
- Application
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别名
K(+) channel subunit beta-2Kv-beta-2 ;hKvbeta2
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13303
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表达区间
1-367aa
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分子量
57 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KCNAB2, a member of the potassium channel auxiliary subunit family, plays a critical role in the modulation of voltage-gated potassium channels by influencing their trafficking, gating properties, and pharmacological characteristics. Research into KCNAB2 has garnered interest due to its potential implications in various physiological and pathological processes, including cardiac and neuronal excitability. Abnormalities in potassium channel function can lead to various diseases, such as arrhythmias and neurological disorders, making KCNAB2 a candidate for therapeutic intervention. Investigating the recombinant expression of KCNAB2 provides insights into its functional characteristics, interactions with other ion channels, and its role in the physiological context. Advances in protein expression techniques allow for the generation of recombinant KCNAB2, enabling detailed studies on its structure and function. Understanding the molecular mechanisms by which KCNAB2 modulates potassium channels may pave the way for novel therapeutic strategies targeting channelopathies. By elucidating the functional dynamics of KCNAB2, researchers aim to contribute to the broader field of ion channel biology, ultimately improving our knowledge of their roles in health and disease.
