Analytical Data
-
基因名
GLCE
- Application
-
别名
Heparan sulfate C5-epimerase ;HsepiHeparin/heparan sulfate:glucuronic acid C5-epimeraseHeparosan-N-sulfate-glucuronate 5-epimerase
-
种属
Human
-
表达系统
E. coli
-
标签
N- His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O94923
-
表达区间
29-617aa
-
分子量
70.9 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of GLCE (Glucosaminoglycan Epithelial Growth Factor) recombinant protein has gained significant attention in the field of biomedical research due to its crucial role in cellular processes and its potential therapeutic applications. GLCE is an enzyme involved in the biosynthesis of heparan sulfate, a type of glycosaminoglycan that is essential for various biological functions, including cell adhesion, growth, and differentiation. Abnormalities in heparan sulfate synthesis have been linked to several diseases, including cancer, cardiovascular disorders, and developmental abnormalities. As a result, understanding the structural and functional properties of GLCE is vital for elucidating its role in these pathologies. Advances in recombinant DNA technology enable the production of GLCE in heterologous systems, facilitating detailed studies of its enzymatic activity and interactions with substrate molecules. Moreover, the development of GLCE as a recombinant protein holds promise for therapeutic strategies aimed at modulating heparan sulfate levels in pathological conditions. By investigating the mechanisms underlying GLCE function and its biosynthesis pathways, researchers aim to uncover novel targets for drug development and enhance our understanding of glycosaminoglycan-related diseases. This research not only contributes to a deeper scientific comprehension but may also lead to innovative treatments that harness the potential of GLCE and its associated pathways in regenerative medicine and disease management.
