Analytical Data
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基因名
HTR3D
- Application
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别名
Serotonin receptor 3D
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q70Z44
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表达区间
221-454aa
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分子量
41.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HTR3D, a member of the serotonin receptor family, has garnered significant attention in recent years due to its pivotal role in neurotransmission and various physiological processes. As a ligand-gated ion channel, it is primarily involved in mediating the effects of serotonin, a crucial neurotransmitter implicated in mood regulation, anxiety, and other neurological functions. Dysregulation of HTR3D has been associated with several neuropsychiatric disorders, making it an attractive target for drug development. Researchers have recognized the potential of recombinant HTR3D proteins for both basic research and therapeutic applications. By producing and characterizing these proteins, scientists aim to elucidate their structural and functional properties, gaining insights into receptor activation mechanisms and signaling pathways. This knowledge could facilitate the design of novel pharmacological agents that selectively modulate HTR3D activity, paving the way for innovative treatments for conditions such as depression and anxiety disorders. Furthermore, the study of HTR3D may also contribute to the broader understanding of serotonin signaling dynamics in the central nervous system, ultimately enhancing our comprehension of brain function and disorders.
