Analytical Data
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Gene name
GPR157
- Application
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Alternative Names
GPR157G-protein coupled receptor 157
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5UAW9
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Expression Region
1-335aa
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Molecular Weight
39.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR157, a member of the G protein-coupled receptor (GPCR) family, has garnered significant attention due to its potential roles in various physiological processes and diseases. GPCRs are critical for cellular communication and play vital roles in signal transduction pathways, making them key targets for therapeutic interventions. Recent studies have implicated GPR157 in modulating neuronal functions, influencing behaviors such as anxiety and depression, and participating in the regulation of food intake and metabolism. Furthermore, emerging evidence suggests that GPR157 may be involved in the pathophysiology of several disorders, including obesity and neurological conditions. The interest in GPR157 has spurred research into its structural biology, signaling mechanisms, and ligand interactions, paving the way for the development of novel pharmacological agents. Understanding the function and regulation of GPR157 through the study of recombinant proteins is essential for elucidating its biological roles and therapeutic potential. By producing and characterizing GPR157 recombinant proteins, researchers aim to investigate its receptor dynamics, signaling pathways, and interaction with ligands, which may ultimately lead to new insights into its contributions to health and disease, as well as the discovery of innovative therapeutic strategies targeting this receptor.
