Analytical Data
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基因名
ADAM6
- Application
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别名
C14orf96; tMDCIV; Adam6a; Disintegrin and metalloproteinase domain-containing protein 6
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种属
Rat
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
G3V9N4
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表达区间
Phe419~Cys664
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分子量
28kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ADAM6, or A Disintegrin and Metalloproteinase 6, is a member of the ADAM family of membrane proteins that plays a crucial role in various biological processes, including cell adhesion, migration, and signal transduction. Its unique structure comprises an active metalloprotease domain, a disintegrin domain, and a cysteine-rich domain, allowing it to interact with other proteins and influence cellular functions. Researchers have increasingly focused on ADAM6 due to its potential implications in several physiological and pathological conditions, including cancer metastasis, inflammation, and neurodegenerative diseases. Studies have shown that ADAM6 is upregulated in certain cancers, suggesting its involvement in promoting tumor progression and invasion. Furthermore, its role in modulating the activity of growth factors and cytokines highlights its significance in tissue remodeling and immune responses. The production of recombinant ADAM6 protein has become a valuable tool for investigating its molecular mechanisms, interactions, and therapeutic potentials. By generating and characterizing recombinant ADAM6, researchers can elucidate its functional roles, explore its enzymatic activity, and assess its potential as a target for therapeutic intervention. The ongoing research into ADAM6 not only enriches our understanding of its biological functions but also opens new avenues for developing novel treatments for diseases where ADAM6 is implicated. As the body of evidence grows, ADAM6 continues to emerge as a significant focus within the fields of biochemistry and molecular biology, warranting further exploration and research.
