Analytical Data
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Gene name
ADAM6
- Application
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Alternative Names
C14orf96; tMDCIV; Adam6a; Disintegrin and metalloproteinase domain-containing protein 6
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Species
Rat
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
G3V9N4
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Expression Region
Phe419~Cys664
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Molecular Weight
28kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ADAM6, or A Disintegrin and Metalloproteinase 6, is a member of the ADAM family of membrane proteins that plays a crucial role in various biological processes, including cell adhesion, migration, and signal transduction. Its unique structure comprises an active metalloprotease domain, a disintegrin domain, and a cysteine-rich domain, allowing it to interact with other proteins and influence cellular functions. Researchers have increasingly focused on ADAM6 due to its potential implications in several physiological and pathological conditions, including cancer metastasis, inflammation, and neurodegenerative diseases. Studies have shown that ADAM6 is upregulated in certain cancers, suggesting its involvement in promoting tumor progression and invasion. Furthermore, its role in modulating the activity of growth factors and cytokines highlights its significance in tissue remodeling and immune responses. The production of recombinant ADAM6 protein has become a valuable tool for investigating its molecular mechanisms, interactions, and therapeutic potentials. By generating and characterizing recombinant ADAM6, researchers can elucidate its functional roles, explore its enzymatic activity, and assess its potential as a target for therapeutic intervention. The ongoing research into ADAM6 not only enriches our understanding of its biological functions but also opens new avenues for developing novel treatments for diseases where ADAM6 is implicated. As the body of evidence grows, ADAM6 continues to emerge as a significant focus within the fields of biochemistry and molecular biology, warranting further exploration and research.
