Analytical Data
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基因名
CADM3
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简介
CADM3 protein plays a key role in cell-cell adhesion and is involved in a series of adhesion activities. It forms calcium-independent homophilic and heterophilic interactions with IGSF4, NECTIN1 and NECTIN3, demonstrating its versatility. CADM3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CADM3 protein, expressed by HEK293 , with C-His labeled tag.
- Application
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别名
Cell adhesion molecule 3; IgSF4B; NECL-1; Syncam3
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种属
Mouse
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99N28
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表达区间
N23-H328
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蛋白长度
Extracellular Domain
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分子量
37-42 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CADM3, or Cell Adhesion Molecule 3, is a member of the immunoglobulin superfamily that plays a crucial role in cell-cell adhesion, particularly in the nervous system. It has been implicated in various biological processes such as neurodevelopment, synaptic plasticity, and potentially in the pathology of neurodegenerative diseases. Recent studies have highlighted its involvement in neuronal migration and the formation of synaptic connections, making it a target of interest for understanding neural circuitry and function. The reorganization of CADM3 as a recombinant protein allows researchers to delve deeper into its structure-function relationships and to explore its potential as a therapeutic target in neurological disorders. By producing CADM3 in a recombinant form, scientists can investigate its interactions with other cellular components, monitor its effects on cellular dynamics, and assess its therapeutic potentials. Furthermore, understanding CADM3's role in pathological conditions could lead to insights for developing novel strategies in treating diseases where cell adhesion mechanisms are disrupted. Overall, the study of CADM3 recombinant protein is a promising frontier in biomedical research, aiming to unravel the complexities of cell adhesion in health and disease.
