Analytical Data
-
基因名
ABHD6
- Application
-
别名
2-arachidonoylglycerol hydrolase; Monoacylglycerol lipase ABHD6
-
种属
Human
-
表达系统
E. coli
-
标签
N-His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9BV23
-
表达区间
Trp30~Asp337
-
分子量
38kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ABHD6 (abhydrolase domain-containing 6) is a serine hydrolase known for its role in the endocannabinoid system, particularly in the hydrolysis of monoacylglycerols. It has drawn considerable interest in recent years due to its involvement in various physiological and pathological processes, including modulation of pain, appetite, and memory. Research indicates that ABHD6 may play a crucial role in neurodegeneration and inflammatory responses, making it a potential therapeutic target for diseases like Alzheimer's and multiple sclerosis. The protein's enzymatic activity impacts the levels of endocannabinoids, influencing cannabinoid receptor signaling pathways. Additionally, understanding the structure-function relationship of ABHD6 can facilitate the development of selective inhibitors, which could serve as leads for drug discovery. Recombinant ABHD6 proteins have been produced for functional assays and structural studies, allowing for a deeper understanding of its enzymatic mechanism and biological significance. This research not only contributes to our understanding of lipid metabolism and endocannabinoid regulation but also opens avenues for developing novel therapeutics aimed at modulating ABHD6 activity in various disease contexts.
