Analytical Data
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Gene name
GERP
- Application
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Alternative Names
TRIM8; RNF27; Tripartite Motif-Containing 8; Probable E3 ubiquitin-protein ligase TRIM8
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Species
Rat
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
D3ZQE3
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Expression Region
Ile74~Ser319
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Molecular Weight
34kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of GERP (Genomic Evolutionary Rate Profiling) recombinant proteins has gained significant attention in the fields of evolutionary biology and bioinformatics. As researchers seek to understand the molecular mechanisms driving evolutionary change, GERP serves as a key tool for identifying conserved regions within genomes that experience reduced evolutionary rates, indicating potential functional importance. GERP scores provide insights into the evolutionary pressures acting on different genes, helping to differentiate between neutral and selection-driven genetic variations. This is particularly crucial for understanding the roles of proteins in essential biological processes and in the development of diseases. By reconstructing and analyzing recombinant proteins using GERP information, scientists aim to elucidate the functional impacts of evolutionary conservation and to explore how these proteins interact within various biological pathways. Moreover, such studies can enhance our understanding of human genetics and contribute to advancements in personalized medicine by identifying targets for therapeutic interventions based on evolutionary principles. Overall, the exploration of GERP recombinant proteins represents a convergence of genomics, functional biology, and evolutionary studies, offering valuable insights into the complexities of life’s evolutionary history and its implications for modern science.
