Analytical Data
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Gene name
SCUBE3
- Application
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Alternative Names
CEGF3; CUB Domain And EGF-Like Repeat Containing 3; Signal peptide, CUB and EGF-like domain-containing protein 3
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IX30
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Expression Region
Glu807~Lys993
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Molecular Weight
26kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SCUBE3 (Signal peptide, CUB domain, EGF-like 3) is a significant protein involved in various biological processes, including cell signaling, developmental biology, and tumorigenesis. Studies have shown that SCUBE3 plays a critical role in the regulation of the WNT/β-catenin signaling pathway, which is crucial for embryonic development and cellular differentiation. Dysregulation of SCUBE3 has been implicated in several cancers, making it an important target for therapeutic research. The protein is characterized by its unique structure, featuring multiple CUB and EGF-like domains, which contribute to its interactions with other proteins and influence cellular functions. Understanding the mechanisms underlying SCUBE3's actions at a molecular level is essential for elucidating its role in normal physiology and disease. Therefore, research efforts are increasingly focused on the recombinant expression of SCUBE3, allowing for detailed functional studies and potential drug development strategies. Through these advancements, researchers aim to unveil the therapeutic potential of SCUBE3-targeted interventions in cancer and other diseases influenced by aberrant signaling pathways.
