Analytical Data
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基因名
HIST2H2AA3
- Application
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别名
H2AFO; HIST2H2AA; H2A.2; H2A/q; HIST2H2AA4; H2A Histone Family Member O
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6FI13
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表达区间
Met1~Lys130
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分子量
44kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HIST2H2AA3 is a gene that encodes a member of the histone H2A family, playing a crucial role in the packaging and organization of DNA within the nucleus of eukaryotic cells. Histones, including HIST2H2AA3, are vital for the formation of nucleosomes, the fundamental units of chromatin, which help regulate gene expression and maintain genomic stability. The study of HIST2H2AA3 has gained attention due to its implications in epigenetic regulation and cellular processes such as DNA repair, replication, and transcription. Dysregulation of histone proteins, including variants like HIST2H2AA3, has been associated with various diseases, including cancer. Researchers are increasingly focused on understanding the specific roles and mechanisms of HIST2H2AA3 in epigenetic modifications and its potential as a biomarker for pathological conditions. Advancements in techniques such as CRISPR/Cas9 gene editing, RNA sequencing, and proteomics are facilitating deeper investigations into the functional properties of HIST2H2AA3, aiming to uncover its contributions to cellular homeostasis and its potential therapeutic applications. As the field of epigenetics continues to expand, the study of HIST2H2AA3 offers promising avenues for discovering new insights into gene regulation and the development of innovative treatments for diseases associated with histone modifications.
