Analytical Data
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基因名
PRDM14
- Application
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别名
PR domain zinc finger protein 14
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9GZV8
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表达区间
Glu395~His568
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分子量
49kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PRDM14 is a member of the PR domain-containing protein family and plays a crucial role in germ cell development, embryonic stem cell maintenance, and pluripotency regulation. It is characterized by its ability to function as a transcription factor, influencing gene expression patterns critical for cellular differentiation and development. Research has shown that PRDM14 is vital for maintaining the self-renewal capabilities of embryonic stem cells and is also implicated in the differentiation pathways of primordial germ cells. Given its significance in early developmental processes, PRDM14 has garnered attention in both developmental biology and reproductive medicine. Moreover, its involvement in various cancer types suggests a potential link between aberrant expression of PRDM14 and oncogenesis. The investigation of PRDM14 as a recombinant protein provides insights into its functional mechanisms, regulatory interactions, and potential therapeutic applications. By producing PRDM14 in a controlled environment, researchers can study its biochemical properties, its role in transcriptional regulation, and its effects in cellular models. Such studies are essential for elucidating the complex regulatory networks that govern cellular identity and development. As a focus of ongoing research, the understanding of PRDM14 and its recombinant forms may offer valuable information for developing strategies in regenerative medicine and cancer therapies.
