Analytical Data
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Gene name
ZG16
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简介
The ZG16 protein has a potential role in protein transport and serves as a linker molecule during trans-Golgi network (TGN) particle formation. Its involvement suggests a dynamic role in intracellular protein transport. ZG16 Protein, Human (HEK293, Fc) is the recombinant human-derived ZG16 protein, expressed by HEK293 , with C-mFc labeled tag.
- Application
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Alternative Names
Zymogen Granule Membrane Protein 16; Zymogen Granule Protein 16; hZG16; Secretory Lectin ZG16; ZG16
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Species
Human
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Source
HEK293
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Tag
C-mFc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O60844
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Expression Region
N17-C167
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Protein Length
Full Length of Mature Protein
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Molecular Weight
43.1 kDa.
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZG16, a protein belonging to the C-type lectin family, has garnered attention in recent years due to its potential roles in immune response and gut health. Initially identified as a secreted protein in the small intestine, ZG16 is thought to be involved in the recognition of microbial pathogens and the modulation of immune responses within the gut environment. Its expression is primarily localized to Paneth cells, which are known for their role in maintaining intestinal homeostasis and defending against infections. The study of ZG16 has expanded as researchers investigate its implications in conditions such as inflammatory bowel disease (IBD), where dysregulated immune responses contribute to pathology. Furthermore, ZG16's unique carbohydrate-binding properties suggest a potential role in pathogen recognition and signaling, making it a candidate for therapeutic interventions aimed at restoring gut microbiota balance and promoting intestinal health. These findings underscore the importance of understanding ZG16's function and its mechanisms, paving the way for future studies that could elucidate its contributions to health and disease in the gastrointestinal tract.
