Analytical Data
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基因名
PLA2G4D
- Application
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别名
cPLA2delta; Cytosolic phospholipase A2 delta
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q86XP0
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表达区间
Pro9~Leu120
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分子量
43kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PLA2G4D, also known as Group IV Phospholipase A2, is an important enzyme involved in lipid metabolism and cell signaling pathways. Its primary function includes the hydrolysis of phospholipids to release arachidonic acid, a precursor for various bioactive lipids that play critical roles in inflammation and cell proliferation. Research has highlighted PLA2G4D's involvement in several physiological and pathological processes, including immune responses and cancer development. The enzyme is also implicated in neurodegenerative diseases, where its dysregulation can contribute to neuronal dysfunction. Given its significant roles, recombinant PLA2G4D has become an important tool for studying its enzymatic activity, regulation, and biological effects. Generating this protein in a laboratory setting allows researchers to investigate its molecular mechanisms and potential therapeutic targets, particularly in diseases where PLA2G4D may serve as a biomarker or a druggable target. Understanding the structure-function relationship of PLA2G4D could pave the way for novel interventions in conditions linked to its activity, highlighting the importance of continued research in this field.
