Analytical Data
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Gene name
PLA2G4D
- Application
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Alternative Names
cPLA2delta; Cytosolic phospholipase A2 delta
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Species
Human
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86XP0
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Expression Region
Pro9~Leu120
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Molecular Weight
43kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLA2G4D, also known as Group IV Phospholipase A2, is an important enzyme involved in lipid metabolism and cell signaling pathways. Its primary function includes the hydrolysis of phospholipids to release arachidonic acid, a precursor for various bioactive lipids that play critical roles in inflammation and cell proliferation. Research has highlighted PLA2G4D's involvement in several physiological and pathological processes, including immune responses and cancer development. The enzyme is also implicated in neurodegenerative diseases, where its dysregulation can contribute to neuronal dysfunction. Given its significant roles, recombinant PLA2G4D has become an important tool for studying its enzymatic activity, regulation, and biological effects. Generating this protein in a laboratory setting allows researchers to investigate its molecular mechanisms and potential therapeutic targets, particularly in diseases where PLA2G4D may serve as a biomarker or a druggable target. Understanding the structure-function relationship of PLA2G4D could pave the way for novel interventions in conditions linked to its activity, highlighting the importance of continued research in this field.
