Analytical Data
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Gene name
NDRG2
- Application
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Alternative Names
SYLD; Nmyc downstream-regulated gene 2 protein
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Species
Rat
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8VBU2
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Expression Region
Ala2~Pro300
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Molecular Weight
37kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NDRG2 (N-myc downstream-regulated gene 2) is a member of the NDRG family of proteins, which are known to be involved in various cellular processes, including differentiation, proliferation, and response to stress. The study of NDRG2 has gained considerable attention due to its potential role as a tumor suppressor and its involvement in multiple cancers, such as prostate, breast, and colorectal cancers. Research indicates that NDRG2 may modulate key signaling pathways that regulate cell growth and survival, highlighting its importance in oncogenesis. In addition, NDRG2 is implicated in neuronal function and has been associated with neurodegenerative diseases, suggesting a multifaceted role in both cancer biology and neurobiology. Understanding the functional mechanisms of NDRG2, particularly through the development of recombinant proteins, can provide valuable insights into its biological roles and therapeutic potential. Thus, the recombinant expression and characterization of NDRG2 are critical for elucidating its mechanisms of action, exploring its diagnostic and prognostic value in cancer, and potentially identifying novel strategies for targeted therapies. This research background underscores the significance of NDRG2 in both cancer and neuroscience, making it a compelling target for further investigation.
