Analytical Data
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基因名
UACA
- Application
-
别名
NUCLING
-
种属
Human
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表达系统
E. coli
-
标签
N-His
-
纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BZF9
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表达区间
Ala29~Glu209
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分子量
23kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
UACA (Uveal Autoantigen Component A) is a protein associated with uveal melanoma, a malignant tumor of the eye that poses significant challenges for diagnosis and treatment. Research into UACA has been propelled by its potential role as a biomarker for early detection of uveal melanoma and its implications in immunotherapy. Uveal melanoma is relatively rare but notorious for its aggressive nature and high rate of metastasis, often spreading to the liver, making early intervention crucial. Recent studies have focused on the structural and functional properties of UACA, highlighting its significance in immune responses and tumor microenvironment interactions. The reorganization of UACA protein, through techniques such as crystallography and protein engineering, aims to elucidate its molecular mechanisms and interactions with other cellular components. Understanding these aspects could pave the way for novel therapeutic strategies that harness the immune system to combat this malignancy or improve diagnostic methods to facilitate earlier detection. As research progresses, the exploration of UACA's multifaceted roles in uveal melanoma and other cancer types remains pivotal in the quest for effective cancer management and immunotherapeutic options.












