Analytical Data
-
Gene name
AHNAK
- Application
-
Alternative Names
AHNAKRS; AHNAK Nucleoprotein; Neuroblast differentiation-associated protein AHNAK
-
Species
Human
-
Source
E. coli
-
Tag
N-His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q09666
-
Expression Region
Met1~Asp300
-
Molecular Weight
40kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
AHNAK is a large scaffold protein that plays a pivotal role in cellular processes, including cell migration, adhesion, and differentiation. It is predominantly expressed in various tissues, including the brain, where it is implicated in neurodevelopment and synaptic plasticity. Research on AHNAK has gained traction due to its involvement in several pathological conditions, including cancer and neurodegenerative diseases. The protein’s unique domain structure, containing multiple protein interaction motifs, suggests that it may serve as a hub for signaling pathways, thereby influencing cellular functions. Given its potential as a therapeutic target, the recombination and functional characterization of AHNAK protein have become crucial in understanding its precise biological roles and mechanisms. Recent studies have focused on producing recombinant AHNAK to investigate its interactions with other cellular proteins and decipher its contributions to disease progression. Moreover, the ability to analyze AHNAK in a controlled laboratory setting facilitates insights into its structure-function relationships, making the study of its recombinant forms essential for advancing our understanding of its role in health and disease. Overall, the research surrounding AHNAK and its recombinant proteins is vital for uncovering novel therapeutic strategies and enhancing our comprehension of protein networks in cellular dynamics.
