Analytical Data
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Gene name
AHRR
- Application
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Alternative Names
AHH; AHHR; BHLHE77; Aryl Hydrocarbon Receptor Regulator; Class E basic helix-loop-helix protein 77
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Species
Human
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
A9YTQ3
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Expression Region
Met1~Pro182
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Molecular Weight
50kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
AHRR (Aryl Hydrocarbon Receptor Repressor) is a crucial protein involved in the regulation of the aryl hydrocarbon receptor (AHR) pathway, which plays a significant role in mediating the effects of environmental pollutants, such as dioxins and polycyclic aromatic hydrocarbons. The research into AHRR is particularly important due to its potential implications in various biological processes, including immune response, cellular growth, and differentiation. Dysregulation of the AHR signaling pathway has been associated with several pathologies, including cancer, metabolic disorders, and developmental issues. AHRR functions primarily as a transcriptional repressor, counteracting AHR activation by binding to the same response elements in DNA, thereby inhibiting the expression of AHR-target genes. Understanding the mechanisms underlying AHRR's action and its interaction with AHR is crucial for developing therapeutic strategies targeting AHR-related diseases. Moreover, recent studies have highlighted the potential role of AHRR in modulating the effects of environmental toxins and its contribution to individual susceptibility to exposure-related health effects. Research on AHRR and its recombinant forms has enabled scientists to explore not only its biological significance but also its potential application in biomedicine and environmental health. Consequently, the expansion of knowledge surrounding AHRR's function and its implications in various research areas underscores the importance of further studies to elucidate its role in health and disease.
