Analytical Data
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基因名
aMACR
- Application
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别名
RACE; 2-methylacyl-CoA racemase
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UHK6
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表达区间
Ala2~Asn148
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分子量
20kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of aMACR (alpha-methylacyl-CoA racemase) recombinant protein is rooted in its significant role in the metabolism of branched-chain fatty acids and its implications in various diseases. aMACR is an enzyme that catalyzes the racemization of alpha-methylacyl-CoA esters, an important step in the catabolism of specific fatty acids, particularly those derived from dietary sources. Mutations in the ACOX1 gene, which encodes aMACR, have been linked to disorders in fatty acid metabolism, such as adrenoleukodystrophy and certain types of cancer. Understanding aMACR's functional mechanisms and its regulation can provide insights into metabolic pathways that are crucial for energy production and the synthesis of bioactive lipids. Moreover, research on the recombinant form of this enzyme has allowed for the detailed investigation of its kinetic properties and structural characteristics, paving the way for potential therapeutic applications and the development of novel biomarkers for disease diagnosis. As such, the exploration of aMACR and its recombinant protein serves as a critical focal point for advancing metabolic biology and understanding the intricacies of lipid metabolism in health and disease.
