Analytical Data
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Gene name
NUSAP1
- Application
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Alternative Names
LNP; ANKT; NuSAP1; SAPL; BM037; Q0310
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BXS6
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Expression Region
Gly237~Gln382
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Molecular Weight
21kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NUSAP1 (Nuclear spindle assembly protein 1) is a crucial component implicated in cell cycle regulation and mitotic processes. It plays a vital role in spindle assembly, chromosome alignment, and segregation during mitosis, ensuring accurate cell division. Abnormal expression or dysfunction of NUSAP1 has been linked to various cancers, suggesting its potential as a biomarker for tumor progression and a target for therapeutic intervention. Research has increasingly focused on the characterization of NUSAP1 recombinant protein to understand its structural and functional dynamics in cellular processes. The production of this protein in a recombinant form allows for detailed study of its biophysical properties and interactions with other cellular components. Additionally, investigating NUSAP1's role in mitosis may reveal insights into cancer biology and identify novel avenues for treatment. Given the growing recognition of the importance of mitotic regulators in oncogenesis, the study of NUSAP1 is vital for advancing our understanding of cell cycle checkpoints and their implications in cancer therapies. By elucidating the molecular mechanisms governing NUSAP1 functionality, researchers aim to leverage this knowledge for significant advancements in cancer diagnostics and therapeutics.
