Analytical Data
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基因名
ZFHX1A
- Application
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别名
ZEB1; AREB6; BZP; NIL-2A; ZEB; ZFHEP; TCF8; NIL-2-A zinc finger protein; Zinc Finger E-Box Binding Homeobox 1; Represses Interleukin 2 Expression; Transcription Factor 8
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P37275
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表达区间
Tyr904~Ala1124
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分子量
34kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZFHX1A, a member of the ZF class of transcription factors, plays a critical role in various biological processes, including developmental regulation and cell lineage specification. Its expression is tightly regulated during embryogenesis and in adult tissues, suggesting its involvement in key developmental pathways. Recent studies have implicated ZFHX1A in the regulation of epithelial-mesenchymal transition (EMT), a process crucial for tissue remodeling and tumor progression. Abnormal expression of ZFHX1A has been associated with several types of cancer, highlighting its potential as a biomarker and a therapeutic target. The recombinant protein of ZFHX1A has garnered attention for its potential to elucidate the molecular mechanisms underlying its function and its interactions with other signaling pathways. By producing ZFHX1A as a recombinant protein, researchers aim to investigate its binding properties, post-translational modifications, and role in transcriptional regulation, thus paving the way for future therapeutic strategies that target ZFHX1A-related pathways in disease contexts. Understanding the functional dynamics of ZFHX1A through recombinant protein studies may also contribute to the development of novel cancer treatments, ultimately improving patient outcomes.












