Analytical Data
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基因名
TKTL1
- Application
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别名
TKR; TKT2; TK 2; Transketolase-related protein; Transketolase 2
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P51854
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表达区间
Met1~Asp259
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分子量
59kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TKTL1 (transketolase-like 1) is an enzyme that plays a critical role in the non-oxidative phase of the pentose phosphate pathway, which is essential for cellular metabolism and biosynthesis of nucleotides and amino acids. This enzyme has gained significant attention in recent years due to its upregulation in various types of cancer, suggesting that it may contribute to the metabolic reprogramming associated with tumor growth and survival. Elevated TKTL1 expression has been linked to increased cell proliferation and resistance to apoptosis, thus making it a potential biomarker for cancer diagnosis and prognosis. Researchers have been focusing on the recombinant production of TKTL1 protein to better understand its structure, function, and implications in cancer metabolism. By producing TKTL1 as a recombinant protein, scientists can elucidate its enzymatic characteristics and interactions with other metabolic pathways, allowing for the development of targeted therapeutic strategies. Additionally, studying the recombinant TKTL1 offers insights into its potential role in metabolic disorders beyond cancer, highlighting its significance in pathology and as a possible target for drug development. Through functional assays, structural analysis, and interaction studies, research on TKTL1 may pave the way for novel interventions that could inhibit tumor growth by disrupting its metabolic dependencies. This burgeoning field underscores the importance of TKTL1 in cancer research and its potential as a target for innovative therapeutic approaches.












