Analytical Data
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Gene name
UBQLN4
- Application
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Alternative Names
A1U; UBIN; C1orf6; CIP75; A1Up; Connexin43-interacting protein of 75 kDa; Ataxin-1 ubiquitin-like-interacting protein A1U; Ataxin-1 interacting ubiquitin-like protein
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NRR5
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Expression Region
Met1~Ser601
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Molecular Weight
69kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
UBQLN4, or ubiquitin-like protein 4, is a member of the ubiquitin-like family of proteins that plays a significant role in the regulation of protein degradation and cellular homeostasis. Recent studies have highlighted its involvement in various cellular processes, including proteasomal degradation, autophagy, and stress responses, indicating its potential importance in maintaining cellular functions. Given its essential roles in these pathways, UBQLN4 has been implicated in several diseases, particularly neurodegenerative disorders and cancers, where protein misfolding and aggregation are prevalent. Research on recombinant UBQLN4 has gained traction as scientists aim to understand its structure-function relationship and elucidate the mechanistic insights into its regulatory functions. Through the production of recombinant UBQLN4, researchers can investigate its interactions with other proteins, its post-translational modifications, and its overall impact on cellular health. This work not only aims to elucidate the biological significance of UBQLN4 but also to explore its potential as a therapeutic target for diseases linked to protein homeostasis. By advancing the understanding of UBQLN4's mechanisms and functions, ongoing research contributes to the broader field of protein quality control and its implications in human health and disease.
