Analytical Data
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基因名
MIOX
- Application
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别名
ALDRL6; KSP32; RSOR; Kidney-Specific Protein 32; Aldehyde Reductase(Aldose Reductase)Like 6; Renal-specific oxidoreductase; Myo-inositol oxygenase
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种属
Human
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表达系统
E. coli
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标签
Two N- s, His- & SUMO-
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UGB7
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表达区间
Met1~Trp285
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分子量
46kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MIOX (myo-inositol oxygenase) is an enzyme that plays a critical role in the metabolism of inositol, a vital sugar alcohol that contributes to various cellular processes, including cell signaling, osmoregulation, and the synthesis of phospholipids. Research on MIOX has gained momentum in recent years due to its significance in both physiological and pathological contexts. Dysregulation of inositol metabolism is implicated in several diseases, including diabetes, neurodegenerative disorders, and certain cancers. The recombinant expression of MIOX has emerged as a crucial approach to study its enzymatic properties, regulatory mechanisms, and functional roles in various cellular contexts. By producing MIOX through recombinant techniques, researchers can obtain large quantities of the enzyme for detailed biochemical assays and structural studies, which are essential for understanding its catalytic mechanisms and interactions with substrates. Furthermore, investigating MIOX in the context of disease models can provide insights into its potential as a therapeutic target. As we expand our knowledge of MIOX and its biological implications, the enzyme may reveal novel avenues for intervention in metabolic diseases and other disorders associated with aberrant inositol metabolism.
