Analytical Data
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Gene name
MAT2b
- Application
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Alternative Names
MATIIbeta; TGR; SDR23E1; Short Chain Dehydrogenase/Reductase Family 23E,Member 1; Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NZL9
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Expression Region
Met1~His334
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Molecular Weight
43kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MAT2b, or Methionine Adenosyltransferase 2B, is a critical enzyme involved in the biosynthesis of S-adenosylmethionine (SAM), a universal methyl donor important for numerous biological processes, including methylation of DNA, proteins, and lipids. Research on MAT2b has gained attention due to its significant role in liver metabolism and its implications in various diseases, including liver cancer, metabolic disorders, and neurological conditions. The identification and characterization of MAT2b as a potential therapeutic target stem from its dysregulation in various pathologies. Furthermore, studies have shown that MAT2b expression levels can influence cellular proliferation and apoptosis, thus linking it to tumorigenesis. Recombinant MAT2b protein studies aim to elucidate its structural and functional properties, which can provide critical insights into its enzymatic mechanisms and interactions with substrates and inhibitors. Understanding MAT2b's role at a molecular level is essential for developing specific modulators that could serve as therapeutic agents in disorders associated with SAM metabolism. The ongoing research in recombinant protein production of MAT2b not only facilitates a deeper understanding of its biological functions but also opens avenues for novel treatment strategies targeting SAM-related pathways.
